Breast Cancer Vaccine Being Tested
By: Charlotte Ames
Updated: April 27, 2012
Kellie Trombitas is a fighter. She underwent both chemotherapy and radiation to knock-out breast cancer over ten tough months. Now, she's excited to be cancer free. But Kellie still has concerns.
So she's taking part in a clinical trial to test E-75 a vaccine to help protect breast cancer survivors from recurrence. E-75 is a part of the HER-2 Neu protein which helps stimulate T-cells to attack cancer cells.
In trials, women injected with the vaccine saw a 50-percent reduction in recurrence. The drug Herceptin can do the same but in a different way.
Only 20% of breast cancer survivors, those with high levels of HER-2, can take Herceptin. E-75 developer George Peoples says three times as many survivors could benefit from his vaccine. It targets women like Kellie, who have lower levels of HER-2.
Doctor Peoples explained, "it allows us to use the vaccine for patients who are otherwise not eligible to receive Herceptin."
Kellie's still getting stronger, fighting to keep cancer from making a comeback.
Doctor Peoples says one day the vaccine could be used to fight lung, prostate and ovarian cancers that also express the her-2 protein.
Conemaugh Memorial in Johnstown is the one site in Pennsylvania that's still recruiting for the breast cancer vaccine trial.
For more information on the breast cancer vaccine trial.



Charlotte Ames is the area's only local Health Reporter and brings you the latest medical health news weeknights. You can catch Healthcast on WTAJ News at 5:00pm and her Health Headlines report on WTAJ News at 5:30pm.