Pigment in the skin provides important contrast data. The signals from the reflected light are picked up by a detector and analyzed by a computer, which displays the information on a screen. Since melanomas arise from the pigmenting cells, the technique can readily pick up scattered differences in cell pigmentation throughout the lesion. Thus, the technique enables physicians to get a closer look at the actual cells beneath the skin.
Researchers have only just begun to study the value of CSLM for melanoma. More studies need to be done to help doctors learn how to use the technology to differentiate between melanoma and benign moles.